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Management of abnormal findings in Pap test results of women vaccinated with the cervical cancer vaccine
 
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Department of Midwifery, School of Health and Care Sciences, University of West Attica, Athens, Greece
 
 
Publication date: 2025-10-24
 
 
Corresponding author
Giannoula Kyrkou   

Department of Midwifery, School of Health and Care Sciences, University of West Attica, Athens, Greece
 
 
Eur J Midwifery 2025;9(Supplement 1):A74
 
ABSTRACT
Overview:
Cervical cancer, historically prevalent in women, has witnessed a decline in incidence and mortality rates with the introduction of Pap tests and screening programs. Human Papillomavirus (HPV) vaccination, a primary preventive measure, offers further promise in reducing the burden of cervical cancer. However, global variations in screening and vaccination coverage persist, necessitating a comprehensive understanding of the effectiveness of these preventive measures. This study aims to compare cervical cytology findings between vaccinated and unvaccinated women, addressing critical research questions related to age, vaccination barriers, infections, and cancer staging.

Aims and Objectives:
This study aims to assess and compare cervical cytology findings, including cytology and colposcopy, among vaccinated and unvaccinated women. Specific research questions explore the impact of age on cervical cancer screening awareness, the correlation between infections and cervical cancer risk, and factors contributing to the stage of cervical cancer at diagnosis.

Method:
Data for this study were obtained from medical records and cervical cytology findings of 98 women collected from a gynecology clinic. The sample included both vaccinated and unvaccinated individuals, and the analysis employed statistical tools within the SPSS software. Variables such as age, vaccination status, time since vaccination, further testing, other infections, and the stage of cervical cancer at diagnosis were examined.

Results:
The study revealed a concentration of individuals in the 15-35 age group, with 49% of the sample over the age of 35. Vaccination coverage was encouraging, with 65.3% having received the vaccine. However, 34.7% remained unvaccinated, indicating potential gaps in awareness. Further analysis highlighted a significant proportion (40.8%) diagnosed with stage 1 cervical cancer, reinforcing the importance of regular screening. Vaccinated individuals were more likely to undergo further testing, suggesting a proactive health approach.

Conclusion:
The research underscores the effectiveness of vaccination and regular cervical cancer screening in reducing the risk of cancer progression. While encouraging vaccination rates were observed, the study identifies areas for improvement, including increased education and awareness. The correlation between vaccination and the stage of cervical cancer emphasizes the importance of proactive preventive measures. Overall, the findings contribute valuable insights for informing and enhancing cervical cancer prevention and screening strategies, particularly in regions with varying healthcare infrastructure and awareness levels.
eISSN:2585-2906
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