PURPOSE:
General objective:To investigate the relationship between maternal mental health on breastfeeding and infantdevelopment. Specific objectives: 1.- To explore the impact of maternal stress during the perinatal periodon the type and duration of breastfeeding. 2.- To compare microbiome changes on human milk in relation withchildbirth indicators and perinatal mental health on lactant women from Hospital del Mar. 3.- To evaluate the association between breastfeeding andinfant neurodevelopment during the first year of life, compared to other forms of lactation andpostnatal complications.

DISCUSSION:
This study is a observational study, completing health surveys during pregnancy until 24 months postpartum.As inclusion and exclusion criteria, our participants are:- Pregnant women- Over 18 years old- Recruited between 12-16 weeks of gestation- Receiving antenatal care at the research centers. Our sample size is 1200 pregnant women from the research centers, approximately 300 women per center.The study begins with prenatal monitoring starting at 12-14 weeks of gestation and following families during postpartum, meeting at 4 months and 24 months after childbirth.Inside the PhD research, I design different variables and surveys in relation to maternal health,breastfeeding and neurodevelopment. All the variables and testing are ready on the redcapdatabase. For lactation variables we have different questionaries on basal time, 29 weeks ofpregnancy, birth and postpartum.In relation to the first objective, I will analize the results from the validated questionnaires aboutmental health, collect perinatal stress (via self-reports and cortisol levels if available), their expectative about breastfeeding and how evolves during postpartum.For breastfeeding rates and our second objective, I will analyze milk samples in relation to birth(Type of birth, antibiotic use) and mental health (diet, exercise, meditation adherence), collected by validated questionnaires completed on redcap by participants.

EVIDENCE WHERE RELEVANT:
Postpartum is a period of special vulnerability related to maternal mental health

KEY MESSAGE:
This proposal further explore the interactions between breastfeeding, maternal mental health, and infant neurodevelopment, proposing new directions for research. Poster session 4 (Group B)