CONFERENCE PROCEEDING
Critical appraisal of a case of fetal ovarian cyst diagnosed at 29+3 weeks of gestation
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Midwifery Department, School of Health Sciences, International Hellenic University, Sindos, Greece
Publication date: 2025-10-24
Corresponding author
Anastasia Tsiligkiri
Midwifery Department, School of Health Sciences, International Hellenic University, Sindos, Greece
Eur J Midwifery 2025;9(Supplement 1):A79
ABSTRACT
Overview:
Fetal ovarian cysts are rare, with an estimated incidence of 1 in 2,500 live births. Diagnosis
typically occurs in the third trimester via ultrasound or fetal MRI. Cysts are classified as
simple or complex and are thought to result from maternal estrogens, fetal gonadotropins,
and placental chorionic gonadotropin. Risk factors include maternal diabetes, Rh
isoimmunisation, and pre-eclampsia, though no standardized prenatal or neonatal
management exists. This report discusses a case involving a 31-year-old multigravida,
primipara woman with an IVF-conceived female fetus. A large, complex fetal ovarian cyst was diagnosed via ultrasound at 29+3 weeks. Labour was induced at 37+6 weeks due to cyst size and complexity. Postnatal surgery led to the loss of the neonate’s left ovary.
Aims and Objectives:
To critically appraise the management of this case according with the most recent international guidelines and evidence-based practices.
Method:
A literature review was conducted using MEDLINE and Cochrane databases to identify
current evidence-based management options for fetal ovarian cysts.
Results:
Evidence suggests that fetal ovarian cysts alone should not influence the timing or mode of
delivery. While the Fetal Medicine Foundation suggests considering induction at 38 weeks,
there is no clear consensus. The Italian Society of Videosurgery in Infancy offers the only
formal guidelines, outlining options including observation, in utero aspiration, or postnatal
surgery, depending on cyst features. In this case, no known risk factors were present, and IVF as a potential contributor remains unstudied. The indication for induction was not supported by obstetric necessity.
Conclusion:
Fetal ovarian cysts represent a rare prenatal finding. Their presence alone does not typically
necessitate changes in the timing or method of delivery. The primary objective in managing
such cases should be the preservation of ovary and fertility. Decisions regarding intervention should be individualized, guided by cyst characteristics, symptomatology, and evolving evidence-based recommendations.